Jan 26, - Three had numbness of the penis, and one reported erectile dysfunction. Only one of the men's sex partners reported a side effect: a mild burning sensation during intercourse. Emla, from AstraZeneca, is also a mixture of lidocaine and prilocaine. It comes in a cream formulation and must be used with a condom. Lidocaine cream is used to temporarily numb the skin to relieve symptoms such as pain and itching from wounds, haemorrhoids, anal fissures, insect bites and nerve pain. Lidocaine cream can also be used to prevent premature ejaculation by desensitising the penis and glans, helping men to last longer in bed.How to use Lidocaine cream · Dosage.